Biotechnology Course Offerings

ASCI 339  Internship in Animal Science (1–12) (CR/NC)
Selected Animal Science students will spend up to 12 weeks with an approved agricultural firm engaged in production or related business. Time will be spent applying and developing production and managerial skills and abilities. One unit of credit may be allowed for each full week of completed and reported internship. Degree credit limited to 6 units. Credit/No Credit grading only. Prerequisite: Consent of internship instructor.

ASCI 403  Applied Biotechnology in Animal Science (5)
Biotechnology and its role in animal science. Applied techniques in gene identification, purification and amplification. 3 lectures, 2 laboratories. Prerequisite: BIO 151, BIO 153.

ASCI 405  Domestic Livestock Endocrinology (4)
Endocrine system and its role in the homeostasis of the animal. Use of hormones in increasing productivity of domestic animals. Endocrinology of reproduction, growth, metabolism and immunology. Discussions of cost-benefit relationships in the use of hormones. 4 lectures. Prerequisite: VS 223, ASCI 220.

ASCI 406 Applied Animal Embryology (5)
Advanced techniques in embryo manipulation including embryo development, transfer, in vitro fertilization, cryopreservation, embryo biopsy and splitting. Discussions of current advances and ethical consideration in cloning and transgenic animal production. 3 lectures, 2 laboratories. Prerequisite: VS 223; ASCI 351 or DSCI 330 recommended.

ASCI 420  Animal Nutrition (3)
Metabolism of proteins, carbohydrates, lipids, minerals, vitamins and water, and the relationship of nutrient utilization to animal production. 3 lectures. Prerequisite: ASCI 220 and CHEM 212/312 (or CHEM 216/316 and CHEM 217/317).

ASCI 503 Advanced Molecular Techniques in Animal Science                                                                    Advanced molecular laboratory techniques in animal science. Topics include analyses of cellular and metabolic regulation, gene expression, gene activation and regulation, gene construct design, transgenesis, knockout animal models. 2 lectures, 2 laboratories. Prerequisite: ACI 403 or consent of instructor.

BIO 351 Classical and Molecular Genetics (5)
Introduction to transmission genetics and to the structure, function and regulation of proteins and nucleic acids. 5 lectures. Prerequisite: BIO 151, BIO 152, BIO 153, and CHEM 212/312 or CHEM 217/317. Recommended: Biochemistry.

BIO 431 General and Cellular Physiology (4)
Physiological processes in cells and organisms, including membrane phenomena, metabolism, enzyme kinetics, and cellular events associated with excitable cells and tissues. Current theories of biochemical, cellular, and organ system control mechanisms. Classical and current experimental techniques. 2 lectures, 2 laboratories. Prerequisite: BIO 152 or BIO 153, and CHEM 212/312. Recommended: STAT 218.

BIO X347 Bioinformatics I (4)
Introduction to molecular biology databases and computer applications in data mining. Use of computer software for nucleic acid, genome and protein sequence analysis; genetic database tools; industrial applications of bioinformatics; ethical and societal impact of genetic manipulation. 3 lectures, 1 laboratory. Prerequisite: Completion of a course in biology, preferably BIO 111 or BIO 151, or consent of instructor.

BIO X451 Topics in Human Genetics: The Genome Project (2)
The changes in scientific questions brought about by having the full DNA sequence of humans made available. Address of some of the ethical, legal, and social questions raised by the Genome Project. 2 lectures. Prerequisite: A course in genetics.

BOT X449 Plant Biotechnology Techniques (2)
Current plant biotechnology applications. The culture of callus, meristems, nodal segments, protoplasts, and suspensions. Bacterial and plant cell transformation, PCR, Southern blots, macroarrays, DNA sequencing, and marker-assisted selection. Miscellaneous course fee may be required - see Class Schedule. 2 laboratories. Prerequisite: BIO 435 or BIO 351, or consent of instructor.

CHEM 128  General Chemistry (4)
Continuation of CHEM 127. Oxidation-reduction reactions, electrochemistry, kinetics, equilibria, thermodynamics, acids and bases. Intended primarily for students whose majors are in the College of Science and Mathematics. Not open to students with credit in CHEM 125. 3 lectures, 1 laboratory. Prerequisite: CHEM 127.

CHEM 129  General Chemistry (4)
Acid and base equilibria, buffers, transition elements, solubility, complex ions, hybridization, nuclear chemistry. Laboratory study of the chemical properties and semi-micro qualitative analysis of the representative group elements of the periodic table. Intended primarily for students whose majors are in the College of Science and Mathematics. 3 lectures, 1 laboratory. Prerequisite: CHEM 125 or CHEM 128.

CHEM 313  Survey of Biochemistry and Biotechnology (5)
Chemistry of biomolecules including carbohydrates, proteins, fats, vitamins, enzymes and hormones. Basic molecular biology with applications to biotechnology and genetic engineering. Practical intermediary metabolism of prokaryotic and eukaryotic systems. 4 lectures, 1 laboratory. Prerequisite: CHEM 212/312 or equivalent.

CHEM 317  Organic Chemistry II (5)
Reactions and reaction mechanisms of organic halides, alcohols, phenols, epoxides, ethers, carboxylic acids and their derivatives, aldehydes, ketones; acidity and basicity; infrared and NMR spectroscopy. 3 lectures, 2 laboratories. Prerequisite: CHEM 216/316.

CHEM 371  Biochemical Principles (5)
Chemical and physical factors in biological processes. Chemistry and function of major cellular constituents: proteins, lipids, carbohydrates. 4 lectures, 1 laboratory. Prerequisite: CHEM 212/312 or CHEM 217/317. Recommended: CHEM 231/331.

CHEM 375  Molecular Biology Laboratory (2)
(Also listed as BIO 375)

Introduction to techniques used in molecular biology and biotechnology; plasmid DNA extraction, characterization and use in transformation. Gene cloning, southern blotting, reverse transcription, and polymerase chain reaction. 2 laboratories. Prerequisite: MCRO 221 or MCRO 224, and BIO 351 or CHEM 373.

CHEM 474  Protein Techniques Laboratory (2)
Experiments in protein affinity chromatography, electrophoresis and blotting, immunoprecipitation techniques, antibody-enzyme conjugation, and immunoassay. 2 laboratories. Prerequisite: CHEM 313 or CHEM 371.

CSC 448  Bioinformatics Algorithms (4) (Also listed as CPE 448)
Introduction to the use of computers to solve problems in molecular biology. The algorithms, languages, and databases important in determining and analyzing nucleic and protein sequences and their structure. 3 lectures, 1 laboratory. Prerequisite: Consent of instructor or the following: CSC/CPE 103 or BIO 447 and senior standing.

MCRO 221  Microbiology (4) GE B2 & B4
Morphology, metabolism, classification and identification; bacteriology of air, soil, water and foods with applications to industry, agriculture, medicine, and public health. Not open to students with credit in MCRO 224; not for credit for Biology and Microbiology majors. Prerequisite: One quarter of chemistry.

MCRO 433  Industrial Microbiology and Biotechnology (3)
Principles and methods used for production of enzymes, pharmaceuticals, chemicals and food additives using micro-organisms. Topics include screening and strain improvement, regulation of metabolite production, genetic engineering, heterologous gene expression systems, large-scale production and intellectual property. 3 lectures. Prerequisite: MCRO 221 or MCRO 224, BIO 351 or equivalent, CHEM 212/312 or equivalent.

SCM 201  Orientation to Biotechnology (1)
Introduction to the diversity of fields in biotechnology. Applications in agriculture, nutrition, medicine and environmental problems. 1 activity. Prerequisite: BIO 151 and CHEM 316 or CHEM 312.

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